4-Pyrimidinamine, 2-chloro-5-methyl- (9CI)

4-Pyrimidinamine, 2-chloro-5-methyl- (9CI) - Names and Identifiers

Name	4-Amino-2-chloro-5-methylpyrimidine
Synonyms	CHLOROAMINOMETHYLPYRIMIDINE 3,5-dibromo-2,6-dimethylpyridine 2-Chloro-5-methylpyrimidin-4-amine 2-Chloro-5-methyl-4-pyrimidinamine 4-Amino-2-chloro-5-methylpyrimidine 2-Chloro-4-amino-5-methylpyrimidine 4-Pyrimidinamine, 2-chloro-5-methyl- (9CI) 3-(2-CHLOROBENZOYL)-5-METHYLTHIOPHEN-2-AMINE
CAS	14394-70-8
InChI	InChI=1/C5H6ClN3/c1-3-2-8-5(6)9-4(3)7/h2H,1H3,(H2,7,8,9)

4-Pyrimidinamine, 2-chloro-5-methyl- (9CI) - Physico-chemical Properties

Molecular Formula	C5H6ClN3
Molar Mass	143.57
Density	1.349±0.06 g/cm3(Predicted)
Melting Point	232-235°C
Boling Point	334.9±22.0 °C(Predicted)
Flash Point	156.327°C
Solubility	DMSO, Ethyl Acetae, Methanol
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	White to Off White
pKa	2.78±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	1.6
MDL	MFCD02683249

4-Pyrimidinamine, 2-chloro-5-methyl- (9CI) - Introduction

It is an organic compound with the chemical formula C5H6ClN3.

In terms of nature, it is a colorless crystal or crystalline powder, soluble in ethanol, chloroform and alkaline solution, insoluble in water. It has a neutral pH value.

This compound has a variety of uses. In the field of medicine, it is used as an intermediate of chemical drugs, for example, in the synthesis of anticancer drugs and antiviral drugs. In addition, it can also be used as a raw material for dyes, coatings and pesticides.

The preparation method can be obtained by reacting 4-amino -2-methyl pyrimidine with Chloroacetyl Chloride.

Regarding safety information, this compound is generally safe and harmless under normal conditions of use, but personal protective measures should be paid attention to during operation, such as wearing chemical protective gloves and glasses. Avoid contact with skin and eyes, avoid inhaling its dust or gas. During storage and handling, the appropriate chemical safety procedures should be observed. In the event of an accident, appropriate emergency measures should be taken immediately and medical advice should be sought.

Last Update：2024-04-10 22:30:50